Health Care Professionals
Stay Connected, Stay Informed
At Pacific Marine Biotech, we understand the impact of bold and innovative research on the medical community. We also understand the importance of the health care professionals who conduct this essential research and care for their patients daily.
PMB looks to engage with these health care professionals by bringing them into the fold and providing an opportunity to share their latest work with other health care providers, researchers, and professionals.
If you are a health care professional who has questions about Immune12, expanded access, or partnering with us on research and trials, please contact us at info@pacificmarinebiotech.com.
Articles of Interest
A Phase II Trial of TBL 12 Sea Cucumber Extract In Patients With Untreated Asymptomatic Myeloma
Patients with smoldering multiple myeloma (MM) may remain asymptomatic (ASx) for variable amounts of time and are therefore typically monitored without treatment. Chemoprevention trials using thalidomide found prohibitive toxicity and longer follow up is needed for early systemic treatment with lenalidomide/ dexamethasone of high risk ASxMM. Based on encouraging preclinical data with bioactive food supplements in MM curcumin (Blood 2003), resveratrol (Blood 2006), and a component of green tea extract (Blood 2006) many patients are already using these agents without definitive proof of efficacy or safety. Preclinically,
2018 British Journal of Haematology, Toxicity Results
Study Purpose: The study investigated the safety and efficacy of TBL-12 in patients with ASMM.
TBL-12: This is a sea cucumber extract that has shown potential antitumor properties in previous research, including anti-angiogenesis, direct tumor cytotoxicity, and inhibition of osteoclastogenesis.
Participants: Twenty patients with ASMM participated in the study. These patients were characterized as being at high risk for disease progression based on established criteria.
Treatment: Patients ingested 2 units of 20 ml of TBL-12 twice per day, for a total of 80 ml per day.
Does Immune12 contain any toxicity?
Scientific analyses of humans and lab rats show that Immune12 is non-toxic with no detected adverse effects. Our proprietary process gives us the ability to successfully